Complete GI Stool Test + 30-Minute Consult with Dr. Brown
GI Effects Comprehensive Profile from Genova
The GI Stool Test from Genova is a suite of advanced stool tests that provide immediate, actionable clinical information for managing gastrointestinal health. Utilizing cutting-edge technologies and biomarkers, these profiles offer valuable insight into digestive function, intestinal inflammation, and the intestinal microbiome.
Digestion/Absorption, Inflammation/Immunology, and the Gut Microbiome
The overview pages make results interpretation quicker and easier to prioritize treatment and assess microbiome status.
The Most Comprehensive GI Stool Test for Optimal Clinical Utility
SPECIMEN TYPE: STOOL
TURNAROUND TIME: mostly 17 DAYS Some products are not available in New York
Do You Suffer From
The GI Stool Test can reveal necessary information about the root cause of many common gastrointestinal symptoms and non-GI conditions, including:
- Gas
- Bloating
- Indigestion/ reflux
- Abdominal pain/ cramps
- Diarrhea
- Constipation
- Inflammatory Bowel Disease (IBD) [1,2]
- Irritable Bowel Syndrome (IBS) [3,4]
- Atopic dermatitis/ eczema [5,6]
- Allergies [5]
- Autoimmune diseases [7,8]
- Mood disorders (depression) [9,10]
- Joint aches [11,12]
- Diabetes [13,14,15]
- Weight issues [15,16,17,18]
The entire body’s health depends on a healthy gut and gut microbiome.
Gut microbes are codependent with one another, and their human host, and the health of one affects the other. A sizeable volume of research associates a dysbiotic or imbalanced gut microbiome with multiple disease states within and outside the GI tract. [19,20,21]
The diverse metabolic activities of the microbiome ultimately impact the human host, and the human host’s actions ultimately affect their microbiome’s health.
The biomarkers on the GI Stool Test: GI Effects Comprehensive Profile (2200) reflect the 3 critical functions of gut health arranged in the “DIG” formate: Digestion/Absorption, Inflammation/Immunology, and the Gut Microbiome
Digestion/Absorption:
- Pancreatic Elastase-1 is a marker of exocrine pancreatic function.
- Products of Protein Breakdown are markers of undigested protein reaching the colon.
- Fecal Fat is a marker of fat breakdown and absorption.
Inflammation/Immunology:
- Calprotectin is a marker of neutrophil-driven inflammation. Produced in abundance at sites of inflammation, this biomarker has been proven clinically useful in differentiating between Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS). [1,2]
- Eosinophil Protein X is a marker of eosinophil-driven inflammation and allergic response.
- Fecal Secretory IgA is a marker of gut secretory immunity and barrier function.
- The Fecal Occult Blood Test detects hidden blood; the American College of Gastroenterology has recommended fecal immunochemical testing (FIT) as the preferred noninvasive test for colorectal cancer screening/detection.
Gut Microbiome:
- Genova is the first laboratory to introduce an Inflammation-Associated Dysbiosis score and a Methane Dysbiosis score by incorporating our latest published microbiome data analysis.22
- Metabolic indicators, including short-chain fatty acids and beta-glucuronidase, demonstrate the microbiota’s specific and vital metabolic functions.
- Commensal Bacteria demonstrate the composition, abundance, and patterns of gut organisms.
- More than 95% of commensal gut organisms are anaerobic and are difficult to recover by traditional (aerobic) culture techniques.
- GI Effects assesses a set of 24 genera/species that map to 7 significant phyla.
- 16S rRNA gene polymerase chain reaction (qPCR) amplification technique
- Comprehensive microbiome analysis included
- Bacterial and mycology cultures demonstrate the presence of specific beneficial and pathogenic organisms.
- Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) technology is used to identify limitless bacterial and fungal species via culture.
- Bacterial and mycology sensitivities are provided for pathogenic or potentially pathogenic organisms cultured. The report includes effective prescriptive and natural agents.
- Parasitology includes comprehensive testing for all parasites on every parasitology exam ordered.
- GI Effects provides microscopic fecal specimen examination for ova and parasites (O&P), the gold standard of diagnosis for many parasites.
- 6 Real-time Polymerase Chain Reaction (PCR) targets detect common protozoal parasites, including Blastocystis spp., Cryptosporidium parvum/hominins, Cyclospora cayetanensis, Dientamoeba fragilis, Entamoeba histolytica, and Giardia. PCR for organisms is emerging as a highly sensitive method for infectious organism detection.
- Selecting a one-day or three-day sample collection is based on the clinician’s clinical index of suspicion for parasitic infection. A one-day sample will likely be adequate if there is no/low suspicion. For high suspicion, a three-day sample collection is optimal.
Additional Microbiome Module Add-on:
Microbiomix offers metagenomic shotgun/ whole genome sequencing to assess your patient’s complete gut microbiome and its potential function. Microbiomix complements the information provided on the GI Stool Test.
HOW THE TEST WORKS
YOUR PERSONAL HEALTH COACHING CALL
During your one-on-one call, Dr. Brown will assess your symptoms and reasons for doing this lab test. Your coach will explain your lab results, answer any questions you may have, and you will walk away with personalized recommendations according to your GI Stool Test results. These can include:
- A supplement plan
- Dietary guidance
- Sleep guidelines
- Stress reduction techniques
- Detox regimens
- Lifestyle changes
No More Guesswork
Rather than other at-home tests that make you guess the results, Dr. Brown takes the time to assess your results and review them with you step by step. And you can feel confident that the supplements, diet, and lifestyle changes we recommend are the right for your body and health goals.
Order Today Your GI Stool Test
Cost: $1179.00 GI Stool Test Sample + 30-Minute consult
Cost: Additional Microbiome Module Add-on $599.00
FAQ
Is it necessary to stop medications or supplements before testing?
Review information on the Test Preparation GI Stool Test for details on how medications and supplements may impact this test.